There are three operational amplifiers in the circuit of an Instrumentation Amplifier. The input of the differential amplifier is a non-inverting amplifier. For exact measurement of each input data from transduces this circuit provides high input impedance. The basic circuit for instrumentation amplifiers is shown.

The input stage of the inverting amplifier is formed by connecting two non-inverting amplifiers represented as op-amps 1 and 2 in the above figure. The output stage of the instrumentation amplifier is a difference amplifier which is the op-amp 3 in the figure above.

**Working** of Instrumentation Amplifier

The output voltage V_{out} of the difference amplifier is actually the output stage of the instrumentation amplifier. This output voltage Vout is then the difference between the input signals applied at the input terminals.

Let us consider V_{o1} and V_{o2} the output voltages of the two op-amps 1 and 2 respectively. Then the value of voltage V_{out} of difference amplifier is

The value of voltages V_{o1 }and V_{o2} is in terms of the input voltages and resistances. The input stage of the instrumentation amplifier is also shown below.

Consider the value of input voltage as V_{1} at node A. From the virtual ground concept, the value of the voltage at node B will be V_{1 }. At node G the potential will also be equal to V_{1 }.

Consider the value of input voltage as V_{2} at node D. From the virtual ground concept the value of the voltage at node C will be V_{2 }. At node H the potential will also be equal to V_{2 }.

The value of current at input stage is zero because we consider the ideal case. Therefore, the value of current remains same in all the resistors R_{1}, R_{gain} and R_{1}

At node E and F from Ohm’s Law, we can write

As there is no input current at the input stage hence, value of current between node G and H will be

Equating both equations 1 and 2,

The output of the difference amplifier is

Therefore,

In equation 3 we substitute (V_{o1} – V_{o2}) value

The output voltage of an instrumentation amplifier is in the above equation. The value of the overall gain of the amplifier is (R_{3}/R_{2}) {(2R_{1}+R_{gain})/R_{gain}}.

**Advantages**

- Also by varying the value of resistor R
_{gain}the gain of a three op-amp instrumentation amplifier circuit can be easily varied and controlled without changing the circuit structure. - The value of gain of the amplifier depends upon the external resistor. Then by choosing the resistor value carefully we can easily set the gain.
- As the non-inverting amplifiers form the input stage of the instrumentation amplifier. The value of input impedance of a non-inverting amplifier is very high.
- The value of the output impedance of the difference amplifier is low and this also the output stage of the instrumentation amplifier.
- Since the value of CMRR of the op-amp 3 is very high because of which almost all of the common mode signals will be rejected.

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